ANCESTRY SPECIFICITY

A closed-loop overlap wheel with 32 combinations, non-hierarchical branches.

All-contig ancestry overlap wheel
Circular UpSet-style map

All-contig ancestry-overlap wheel

Every graph-rescued contig appears once. All 32 exact combinations are arranged in a closed Gray-code loop, with adjacent sectors differing by a single ancestry membership.

6,233 individual contigs32 exact combinations4,239 supported across all five482 with no tagged overlap

Closed-loop support map

Dot color shows breadth of support. Five outer rings identify the exact ancestry strata.

Interpretation. This figure describes overlap in alignment support. It does not by itself demonstrate interaction, gene flow, admixture, or evolutionary ancestry. “Graph-rescued” is the workbook’s source-set description; the workbook lacks a per-contig GRCh38-only failure benchmark.

Dream it

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Dream it 〰️

apgContigs overlap tree
Descriptive support-profile clustering

apgContigs ancestry-overlap tree

A phylogeny-like view of correlated alignment support. Branch length is generalized-Jaccard dissimilarity between continuous ancestry-stratum prevalence profiles; it is not evolutionary time, lineage, or genetic ancestry distance.

Continuous alignment-support landscape

Each row is a unique five-stratum prevalence signature, weighted by the number of contigs sharing it. Columns show the fraction of QC-eligible samples supporting that signature.

0100%
Method. Support prevalence was calculated from the individual matrix after excluding all-zero sample HG00272 (denominators: AFR 70, AMR 44, EAS 50, EUR 29, SAS 36). The 989 unique nonzero prevalence signatures were clustered with generalized Jaccard distance and average linkage. The 482 zero-support contigs are kept in a separate unresolved group because their mutual Jaccard distance is undefined and observed absence may be technical.
Population contig-overlap tree
Twenty-seven population support profiles

Population tree from contig overlap

Populations are joined by similarity in continuous contig-support prevalence. This is a descriptive support tree, not a population phylogeny, evolutionary history, or estimate of genetic ancestry distance.

Support-profile dendrogram and overlap matrix

Node percentages are sample-resampling stability. Matrix cells show generalized-Jaccard similarity.

Method. For each population, every contig was represented by the fraction of QC-eligible assemblies supporting it. Pairwise generalized Jaccard overlap ignores joint absence and retains both prevalence magnitude and sharing. Average linkage forms the tree. Node stability is exact-cluster recurrence across 250 within-population sample bootstraps. HG00272 is excluded.